Clinical effects of collagen hydrolysates ingestion on UV-induced pigmented spots of human skin:

A preliminary study

Fumihito SUGIHARA, Naoki INOUE

(Nitta Gelatin Inc., Peptide Division)

ABSTRACT

To examine the effects of ingesting collagen hydrolysates（CHs） from fish scale（fish CH）and swine skin（swine CH）on UV-induced pigmented spots（UV spots）of human skin, a placebo controlled randomized double blind study was conducted. Thirty-nine females ingested 5 g each of control food, fish CH or swine CH daily for 8 weeks. A within-group comparison showed that both fish and swine CHs significantly decreased the area of UV spots between before and 8 weeks after ingestion. In particular, swine CH significantly decreased the area from an early period of 4 weeks after ingestion.